Publications

35. Demirsoy, Z; Kesici, M.S.; Özçubukçu, S.; Gülseren, G.* Self-Assembled Peptide Nanofiber-Based Nanopharmaceutics for the Treatment of Viral Infections. Under Revision.

34. Soyler, D.; Dolgun, V; Kurbanoglu, S.; Özçubukçu, S.; Söylemez, S.* Synthesis and design of functional fullerenol-based electrochemical nanobiosensor to examine the inhibition effects of anti-Alzheimer drug active Pyridostigmine on Acetylcholinesterase. Under Revision.

33. Soyler, D.; Dolgun, V.; Cetin, Ö.; Khan, Y.; Güler Çelik, E.; Özçubukçu, S.; Unalan, H.; Timur, S.; Soylemez, S.* Surface Engineering of MXene and Functional Fullerenols for Cancer Biomarker ‘EIF3D. 2025, Langmuir, Accepted. DOI: 10.1021/acs.langmuir.5c00157

32. Schmidt, H.; Chalil Oglou, R.; Tuncer, H.; Ulusoy G. T.; Tekir, Ş.; Ozvural-Sertcelik, K.; Ibrahim, A.; Döhler, L.; Özçubukçu, S.; Kupfer, S.; Dietzek-Ivanšić, B.; Karadas, Ferdi*. A Heterodox Approach for Designing Iron Photosensitizers: Penta-cyanoferrate(II) Complexes with Monodentate Pyridinium-Based Acceptor Ligands. 2025, Inorganic Chemistry. Accepted.

31. Zare, D.; Yılmaz, G.; Özçubukçu, S.* Application of Redox-Responsive Cysteine-Based Organogels as a Drug Delivery System for DoxorubicinACS Omega, 2025, 10, 147–156.

30. Şentürk, H.*; Dedeakayoğulları, H.; Marion, İ. U.; Özçubukçu, S.; Kesici, M. S.; Ünsal Beyge, Ş.; Acar, M.; Erkısa, M. G.; Akbas, F; Ulukaya, E. Human estrogen receptor alpha (ERα) targeted cyclic peptides inhibit cell growth and induce apoptosis in MCF-7 cellsTurk. J. Biochem. 202449, 542-550.

29. Oglou, R. C., Ghobadi, T. G. U., Saylam, A., Bese, D., Bese, C., Yaglioglu, H. G., Özçubukçu, S.; Özbay, E.; Karadaş, F.* Rational design of an acceptor–chromophore–relay–catalyst tetrad assembly for water oxidationChem. Commun.2024, 60, 1707-1710.

28. Gülyüz, S.; Sessevmez, M.; Ukuser, G.; Khalily, M. P.; Tiryaki, S.; Sipahioglu, T.; Birgul, K.; Ömeroğlu İ,; Özçubukçu, S.; Telci, D.; Kucukguzel, S. G.; Durmus, M,; Cevher, E.; Yılmaz, Ö. A Novel PEtOx‐Based Nanogel Targeting Prostate Cancer Cells for Drug DeliveryMacromolecular Bioscience, 2024, 24, 2300324.

27. Soylemez, S.*; Dolgun, V.; Özçubukçu, S.* Fullerene-based mimics of enhanced acetylcholine detection for the diagnosis of Alzheimer’s diseaseMicrochem. J.2023, 193, 109099.

26. Soydan, M.; Okyar, B.; Zorlu, Y.; Marion, A.; Özçubukçu, S.* (2023). Tetraphenyl-1, 4-dioxin and Tetraphenyl-pyrane-4-one: Old Molecules, New InsightsACS Omega2023, 8, 19656-19662.

25. Khan, A.; Ozcelik, C. E.; Begli, O.; Oguz, O.; Kesici, M. S., Kasırga, T. S., Özçubukçu, S.; Yuca, E.*; Seker, U. O. S*. Highly Potent Peptide Therapeutics To Prevent Protein Aggregation in Huntington’s DiseaseACS Med. Chem. Lett.2023,14, 1821-1826.

24. Ozcelik, C. E.; Beğli, O.; Hınçer, A.; Ahan, R. E.; Kesici, M. S.; Oguz, O.; Kasırga, T. S.; Özçubukçu, S.; Seker, U. O. S.* Synergistic screening of peptide-based biotechnological drug candidates for neurodegenerative diseases using yeast display and phage displayACS Chem. Neurosci. 2023,14, 3609-3621.

23. Cevheroğlu, O.*; Demir, N.; Kesici, M. S.; Özçubukçu, S.; Son, Ç. D. Downstream signalling of the disease‐associated mutations on GPR56/ADGRG1Basic Clin. Pharmacol. Toxicol.2023, 133, 331-341.

22. Yeniterzi, D.; Demirsoy, Z.; Saylam, A.; Özçubukçu, S.; Gülseren, G.* Nanoarchitectonics of Fullerene‐Based Enzyme Mimics for Osteogenic Induction of Stem CellsMacromol. Biosci., 2022,  22, 2200079.

21. Gulyuz, S.; Bayram, D.; Ozkose, U. U.; Bolat, Z. B.; Kocak, P.; Saka, O. M.; Devrim, B.; Parlak-Khalily, M.; Telci, D.; Şahin, F.; Özçubukçu, S.; Sezer, E.; Taşdeler, M. A.; Alptürk, O, Bozkır, A.; Yilmaz, O. *Synthesis, biocompatibility and gene encapsulation of poly (2-Ethyl 2-Oxazoline)-dioleoyl phosphatidylethanolamine (PEtOx-DOPE) and post-modifications with peptides and fluorescent dye coumarin. Int. J. Polym. Mater. 2021, 70, 981-993.

20. Gulseren, G.; Saylam, A.; Marion, A.; Özçubukçu, S.*. Fullerene-based mimics of biocatalysts show remarkable activity and modularity. ACS Appl. Mater. Interfaces, 202113, 45854-45863.

19. Ozkose, U. U.; Gulyuz, S.; Parlak Khalily, M.; Özçubukçu, S., Bozkir, A.; Tasdelen, M. A.; Alptürk, O.; Yilmaz, O.* The synthesis of peptide‐conjugated poly (2‐ethyl‐2‐oxazoline)‐b‐poly (L‐lactide)(PEtOx‐b‐PLA) polymeric systems through the combination of controlled polymerization techniques and click reactions. J. Appl. Polym. Sci., 2021138, 50286.

18. Nezir, A. E.; Khalily, M. P.; Gulyuz, S.; Özçubukçu, S., Küçükgüzel, Ş. G., Yilmaz, O.; Telci, D.* Synthesis and evaluation of tumor-homing peptides for targeting prostate cancer. Amino Acids2021, 53, 645-652

17. Oz, U. C.; Bolat, Z. B.; Ozkose, U. U.; Gulyuz, S.; Kucukturkmen, B., Khalily, M.P.; Özçubukçu, S.; Yilmaz, O.; Telci, D.; Esendagli, G.; Sahin, F., A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomesMaterials Science and Engineering: C, 2021123, p.111929.

16. Gulyuz, S.; Ozkose, U. U.; Khalily, M. P.; Kesici, M. S.; Kocak, P.; Bolat, Z. B.; Kara, A.; Ozturk, N,; Özçubukçu, S.; Bozkir, A.; Alpturk, O.; Telci, D.; Sahin, F.; Vural, I.; Yilmaz, O. Poly (2-ethyl-2-oxazoline-co-ethyleneimine)-block-poly (ε-caprolactone) based micelles: synthesis, characterization, peptide conjugation and cytotoxic activityNew Journal of Chemistry2021, 45, 14532-14547.

15. Aykent, G.; Zeytun, C.; Marion, A.; Özçubukçu, S.* Simple Tyrosine Derivatives Act as Low Molecular Weight Organogelators” Scientific Reports, 2019, 9: 4893.

14. Parlak, M; ÖzçubukçuS.* Design and Synthesis of a Photocontrolled Peptide Based Potential Drug Carrier” Turk. J. Chem.  201842, 1136-1145.

13. Onat, B.; ÖzçubukçuS.; Banerjee, S. Erel-Goktepe, I. “Osteoinductivity of poly(4-hydroxy-L-proline ester) (PHPE) and osteoconductivity of PHPE-based layer-by-layer films” Eur. Polym. J. 2018, 103, 101-115

12. Parlak, M.; Gerekçi, S.; Güleç, E. A.; Özen, C. Özçubukçu, S.* Structure-Based Design and Synthesis of Killer Cyclic Peptides for Multiple Myeloma Tumor Cells” Amino Acids, 2018, 50, 1607-1616.

11. Soylemez, S.; Yılmaz T.; Buber, E.; Udum Y. A.; Özçubukçu, S.;* Toppare, L* “Polymerization and biosensor application of water soluble peptide-SNS type monomer conjugate” J. Mat. Chem. C. 20175, 7384.  

10. Soylemez, S.; Demir, B.; Eyrilmez, G. O.; Kesici, S.; Saylam, A.; Demirkol, D. O.; Özçubukçu, S.; Timur, S.; Toppare, L. “Comparative cell adhesion properties of cysteine extended peptide architectures” RSC Advances, 6, 2016, 2695.

9. Zhou, L.; Bosscher, M.; Zhang, C.; Özçubukçu, S.; Zhang, L.; Zhang, W.; Liu, J.; Li, C. L.; Jensen, M. P.; Lai, L.; He, C. “A protein engineered to bind uranyl selectively and with femtomolar affinity” Nature Chemistry, 20146, 236.  (News in C&EN)

8. Beemelmanns, C., Husmann, R., Whelligan, D.K., Özçubukçu, S., Bolm, C. “Planar Chiral Disilanols and Diols as H-Bonding Asymmetric Organocatalysts” Eur. J. Org. Chem. 2012, 3373.

7. Özkal, E., Özçubukçu, S.; Jimeno, C.; Pericas, M.A. “Covalently Immobilized tris(triazolyl)methanol–Cu(I) Complexes: Highly Active and Recyclable Catalysts for CuAAC Reactions” Catal. Sci. Technol.20122, 195.

6. Özçubukçu, S.; Wegner, S.; Mandal, K.; Jensen, M. P.; He, C. “Selective Recognition of Americium by Peptide-Based Reagents Inorg. Chem. 2011, 50, 7937.

5. Özçubukçu, S.; Özkal, E,; Jimeno, C.; Pericas, M. A.” A Highly Active Catalyst for Huisgen 1,3-Dipolar Cycloadditions Based on the Tris(triazolyl)methanol-Cu(I) Structure” Org. Lett2009, 11,4680.

4. Özçubukçu, S.; Schmitt, E.; Leifert, A.; Bolm, C. “A General and Efficient Synthesis of Nitrogen-Substituted Ferrocenes”. Synthesis2007, 389.

3. Özçubukçu, S.; Schmidt, F.; Bolm, C. “Organosilanols as Catalysts in Asymmetric Aryl Transfer Reactions” Org. Lett. 20057, 1407. (“Highlighted in Synfact by Prof. Yamamoto”)

2. Bolm, C.; Schiffers, I.; Atodiresei, I.; Özçubukçu, S.; Raabe, G. “A Novel Asymmetric Synthesis of Highly Enantiomerically Enriched Norbornane-type Diamine Derivatives” New J. of Chem. 200327, 14.

1. Tanyeli, C.; Özçubukçu, S. “The First Enantioselective Synthesis of Chiral Norbornane-type 1,4-Diamine Ligand”. Tetrahedron Asymmetry 200314, 1167.

Other publications

3. Bilir, G., Demir, A. S., Özçubukçu, S.* “Enzyme-Catalyzed Trans-Benzoin Condensation.” J. Turk. Chem. Soc., Sect. A: Chem20185, 737-750.

2. Karaca, U., Kesici, M. S., Özçubukçu, S.* “Synthesis of Chlorotoxin by Native Chemical Ligation.J. Turk. Chem. Soc., Sect. A: Chem20185, 719-726.

1. Alpturk, O.*; Yeşilbaş, Z.; Sarıoğlu, G.; Karaçaylı, A.; Saylam, A.; Özçubukçu, S. “Optimization of synthetic route to PNA-T-OH monomers.” J. Turk. Chem. Soc., Sect. A: Chem20185, 457-468.

Patents

Özçubukçu, S.; Özkal, E,; Jimeno, C.; Pericas, M. A. “Tris (1,2,3-triazol-4-yl) Organometallic Compounds as Catalysts and Processes Using Them” WO 2011/009934 A1

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